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ScienceNo, Plastics Are Not Lowering Your Testosterone Levels - Real Science Explained Inside (self.TheRedPill)

submitted by 2InvoluntarySickCunt

This post is in response to another community member's post that essentially amounts to fear mongering over the use of plastics. The fact that almost no one in the comments, including multiple ECs, questioned the validity of the linked literature is worrying, and illustrates the need for a quick run-down of scientific skepticism.

First off, let me say that bringing up topics like estrogen-mimicking plasticizers is completely valid and important. However, stating that "plastics are the tobacco of the 21st century" without a wealth of credible primary literature is absurd and akin to stating that "water is a chemical in weed-killer so it must be bad for you".

Why you should trust my judgement: I am a molecular biologist and immunologist who is active in the academic sphere and have expertise in in vitro cellular assays. This is a fancy way of saying that I grow lots of cells in plastic dishes and then look at them in different ways, and it's how most of these studies are conducted. Also, it's my job to evaluate academic literature.

Ok let's do this I'll try to make it as entertaining as possible.


Polymer Chemistry - also known as REEEEEEEEEEEEE

As mentioned in the original article, some specific types of plastic polymer are embedded with plasticizers - essentially molecules added to the polymer matrix to change the physical properties of the material. Now most plastics are really just long carbon chains arranged horizontally with some interlinking vertical bonds, kind of like a the lines on a sheet of paper. Plasticizers insert themselves in the spaces between the lines and push them apart, making the material more flexible.

Knowing that there are many types of plastic and many ways of making each type you might ask - "well what kind of plastics should I watch out for? Am I really being dosed by 'big tampon' with endocrine disruptors until I get a period so they can make even more money?" Well big tampon may be trying, but substances recognized as harmful by the primary literature are really only commonly found in the following materials:

  1. Polyvinyl chloride (PVC)
  2. Nitrile (like the rubber gloves your doctor wears for your weekly prostate exam)
  3. Polyesters (this is more of a class of plastics)

Now keep in mind that polymer chemistry is really a black magic in itself and nothing is as simple as, "yes this water bottle will give you bitch tits" or "no this prostate stimulator will not - unless you stick it in your mouth". So instead of going through a list of plastics, of which there are many, and their production methods let's just get to refuting the literature linked in the OP. If you're dying to talk physical chem you can contact me and we can both pretend like we know what's going on after reading wikipedia.


Das Swedish Study

The first claim the article makes is that a Swedish study (n=200) found a correlation between maternal phthalate levels and "anogenital distance" - that's the distance from the anus to the genitals (commonly referred to as the scrote or undercarriage) after 20 months of life.

First of all, you have to go on a wild goose chase to even understand why anogenital distance was used. It's actually a method of measuring reproductive toxicity as the trait is under androgen-receptor control. However, this method is really only used in animal studies and is not commonly applied to humans. Secondly, looking at Table 5 as presented in the study, the researchers present a model of confidence intervals that are not even close to significant. Not only that, but the article provides no evidence that (1) the pthalates in the maternal urine samples measured were from incidental ingestion of plasticizers or that (2) the correlation between maternal pthalate levels and scrote length has anything to do with the correlation between you drinking water out of a microwaved bottle and your dick shrinking up into an infinitesimally dense and small point, birthing a black hole.

This study is completely irrelevant to the original posters point.

Study #2: The Mysterious Case of Shitty Workers' Rights in China

Luckily I didn't even have to waste my time reading deciphering jargon and ugly figures this time around because this isn't even a research paper. It's a huffington post article that literally says half way down the page, "This data should not raise alarm bells for men who don’t work in chemical factories".

The study the article sites was looking at levels of free testosterone in men who worked in a plastic factory in China- now this may be news to some of you guys but working in a Chinese plastic factory with no OSHA to save you is quite a bit different than drinking from a water bottle. And don't worry, we will get to the water bottle data soon enough.

Study #3: Estrogen-dependent proliferation of MCF7 Cells, or, 18 bottles of bitch tits on the wall

This study is the closest thing linked to actually being somewhat valid. In this study an assay is carried out where MCF7 cells are essentially treated with tap water where the solids in it have been concentrated way down from 1.5L to a few mL. For those who don't like commie units that means whatever is in that water is 1500x more concentrated than in your tap water.

Anyway, so to 1500 MCF7 cells is added all the different water "extracts" (this is a highly simplified explanation) and a week or so later they look at the proliferation of the cells. What the hell, you may be asking? Why would you even measure the proliferation of these cells in response to water? Well, as it turns out, MCF7 is an immortal breast cancer cell line that expresses high levels of estrogen receptors and proliferates in response to activation of those receptors. Now if you scroll down to the results you can see that WOAH, the relative proliferation increased almost 80% when the evil dire-aids bottled water was used (but only sometimes when DMSO or dimethylsulfoxide is used as a solvent, which could very well be significant because DMSO makes anything dissolved in it pass through cellular membranes)! Big tampon strikes again boys. But wait... Lets think about this for a second.

This is an assay carried out in a cell culture dish on a cancerous immortal cell line. Now I have a lot of experience with cancerous cell lines, I work with them every day, and I can tell you that these aren't normal cells. Cancerous cell lines are the kind of thing that you can look at the wrong way and they start dividing- it's literally cancer my dudes. Not only that, but the estrogenic activity is only even significant when DMSO is included (although highly diluted), and the water is "concentrated" (look up solid phase extraction if you want in-detail info on this process it's actually fascinating) in a specific way!

Even if we put all of these potential flaws of methodology aside we can see in the results section that the relative estrogenic activity is equal to that of 1-12 picrograms (pg) per liter. For reference, a picogram is 1x10-12 grams. Putting this in perspective, a liter of water from Tampon-Corp has a truly devestating mass of 0.0000000018% the mass of a single grain of fucking sand. Guys. Oh, and that relative increase in proliferation was all that with just 1500 cells (avg. human has upwards of 15 trillion, or 15x1012 cells or 10 factors of 10 more).


Conclusions

Now, my dudes. I understand that not everybody can be or wants to be a scientist. If you don't have first-hand experience working with cells and these kinds of methodologies, there would be no possible way to even read through some of these articles (the first one in particular is grueling as hell). However, we all have a responsibility to think critically about what we're reading instead of jumping to the conclusion that the government wants to cuck you. Think about it, if plastics were a government conspiracy like some of you apparently think, why would they use them on their own fucking armed forces?!

Next time you read something that tells you you're going to get dire-vagina-period-out-your-dickhole, use the following process to assess the evidence:

  1. Look at the model organism in the study. How close is it to human? In scale? Genetically? Is it cancerous? In these cases, rodent models would have been far superior to established cancer cell lines in my opinion.

  2. Read the results section first, the introduction second, and the methods last. Look at the figures, do they look right? Are they clear?

  3. Where is this info coming from? HuffPo? Or is it a legitimate scientific journal. Is it in all Chinese?

  4. Make sure that anyone who disagrees with your uninformed opinions is called a shill, as this argument has been passed down through the ages.

Anyways, my dudes, you're not going to grow bitch tits because you drink out of a water bottle. Is it possible there could be picogram levels of estrogen-mimicking molecules in your water? Yup. But guess what, there's probably about 100x more cockroach jizz in everything you eat, because a picrogram is literally such a small amount that I can't even describe it without scientific notation. So sack up and read the primary literature so you don't look like a dumb ass.

Thanks for reading. Mistakes in this article are a result of late-night writing. -ISC

UPDATE: Many community members have been asking me to provide scientific context to related issues such as steroid use and aluminum in deodorant.

I'm happy to see this kind of curiosity but can't address all of the questions. I've decided to make a series of posts where I will review the literature on a specific topic from both sides in plain speak, as well as demonstrate how to assess the literature without having to have 3 degrees. A huge problem with academia is the jargon that locks the public out of the discussion, and the shoddy quality science "reporting" that makes it to the public. Let's do something about that.

You can vote for the first topic we will address together, or select other and send me a private message with your suggestion.

www.strawpoll.me/13888594

Thank you all and I look forward to continued learning within this unique community.


[–]Do not send modmail to my personal inboxCrazyHorseInvincible[M] [score hidden] stickied comment (6 children)

Pinned.

Remember, the metaphor of the "red pill" is about *seeing what is in front of you, not what you expect to see".

[–]ThePounder 313 points314 points  (60 children)

I clicked the links in the original post and stopped as soon as I saw that the Huffington Post was used as if its a credible (academic) source.

Thanks for clearing this up.

[–]Kinbaku_enthusiast 67 points68 points  (25 children)

Here are some studies that support being careful with BPA from sources other than the huffington post.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280330

http://www.sciencedirect.com/science/article/pii/S0378427410000561

https://academic.oup.com/endo/article/149/3/988/2454992/Bisphenol-A-Prevents-the-Synaptogenic-Response-to

The science is far from settled and it seems there is good cause to be careful.

Let's not forget that there were scientists supporting the thesis in the other post, so your request that people should believe you because you are a scientist just puts us back at square one: which scientist should we believe?

[–][deleted]  (10 children)

[removed]

    [–]antorbug 21 points22 points  (6 children)

    So basically eating store receipts will make you grow tits? Nice.

    [–]Kinbaku_enthusiast 14 points15 points  (0 children)

    No, it is absorbed through the skin.

    [–]Senior Contributordr_warlock 4 points5 points  (0 children)

    The matrix printer reciepts were invented to make us beta males!

    [–]Troll_Name 2 points3 points  (3 children)

    There's a point to all of this, and it isn't that water bottles are safe.

    Rather, the point is that BPA is abso-fucking-lutely everywhere in the developed world. Is it solely responsible for the pussification of the modern male? Of course not, no one factor is solely responsible for a perfect storm.

    [–]metallicdrama 6 points7 points  (2 children)

    Just eat extra red meat and squat more. Problem solved. And if not, you won't give a fuck after anyways.

    [–]Troll_Name 1 point2 points  (1 child)

    If you didn't give a fuck you wouldn't be eating extra red meat and squatting.

    [–]metallicdrama 1 point2 points  (0 children)

    If one did not give a fuck about their T, yes. The idea clearly was that if you're eating red meat and squatting, you won't give a fuck about plastic bottles because your head is already somewhere better. That's so fucking obvious, you're a moron.

    [–]Kinbaku_enthusiast 9 points10 points  (1 child)

    Yes, exactly.

    Your article too contradicts this OP, btw.

    Sidenote: the claim that BPA is no longer used for water bottles isn't accurate. I saw a recent study in my country that more than half of sold water in bottles were bottles that contained BPA.

    Finally it may well be impossible to significantly reduce BPA exposure for individuals at this point, as one of participants of a study in the other post pointed out.

    [–]Imachangin 7 points8 points  (0 children)

    Even if they stopped using BPA in them it seems like everyone and their mom forgets that there's other bisphenol's than bisphenol a that can be used and still called BPA free.

    [–]frankalliance 5 points6 points  (0 children)

    which scientist should you believe?

    Neither. The experiments need to be repeated multiple times until we are certain the results are predictable.

    [–]yomo86 1 point2 points  (11 children)

    Right. Whenever a self-proclaimed scientist with or without experience in his field says something along the lines of: despite contradicting evidence I am right cause X, thus you are wrong, is to be taken with a huge grain of salt.

    We saw T levels dropping in the first and second world, while there is still no conclusive explanation what causes it. So it has to do with modern life. That is all that is for sure.

    [–]Kinbaku_enthusiast 1 point2 points  (5 children)

    I recommend reading further down, because he does make a compelling argument. But yes, I agree, it's healthy to be careful.

    Btw how do we know T levels have dropped?

    [–]yomo86 1 point2 points  (4 children)

    Yes he does make a compelling point but still, I am just skeptical.

    Reduced T-levels made it even into the mainstream: http://uk.reuters.com/article/health-testosterone-levels-dc/mens-testosterone-levels-declined-in-last-20-years-idUKKIM16976320061031

    I don't know to why but making out a correlation with the increase in allergies on a broad scale are to obvious - so it has something to do with modern life.

    [–]Kinbaku_enthusiast 1 point2 points  (2 children)

    1% per year for 4 decades? Something that I will look into deeper, thanks.

    [–]Troll_Name 0 points1 point  (1 child)

    That only suggests 40% if we're talking about percentage points.

    I would call this deceitful sugar-coating.

    [–]Kinbaku_enthusiast 0 points1 point  (0 children)

    Depends if it's cumulative or not, but in either case it's a considerable amount.

    [–]Troll_Name 0 points1 point  (0 children)

    Perfect fucking storm. No one component is the whole.

    Have T levels been dropping the past several decades? Just look outside, if you can find outside. Perfect storm.

    [–]Future_Alpha[🍰] 0 points1 point  (4 children)

    Easy peasy lemon squeezy.

    1. being cucks and cucked society.
    2. lack of exercise/movement
    3. lack of war
    4. corresponding adoption of feminine value traits (empathy/compassion).
    5. large amounts of psychological stress
    6. shit diet

    There are studies that show that behavior influences hormonal levels.

    [–]Gaze73 0 points1 point  (1 child)

    Could be a chicken and egg thing. Low T causes your 6 points and it's a self-reinforcing cycle.

    [–]Future_Alpha[🍰] 0 points1 point  (0 children)

    Low T would definitely cause these behaviors but these behaviors would lead to low T for most guys. Unless they have testicular injury or genetic impotence.

    [–][deleted] 0 points1 point  (1 child)

    large amounts of psychological stress

    lack of war

    i'm sorry what? that seems like a contradiction, war is pretty stressful, even traumatic to the point it causes PTSD.

    [–]Future_Alpha[🍰] 0 points1 point  (0 children)

    Chronic psychological stress has been shown to lead to lower testosterone levels. Unless one doesn't know how to deal with it.

    People get PTSD because they have not learned how to deal with stress and be stress-resistant. Partly this can be attributed to religion and partly to the fact that society has become so 'safe'. In an environment where death and war are part of life - war is not a big deal and will be less likely to cause PTSD. Instead it will bring out the best traits (as well as the worst) in men as it will allow them to be stress resistant (nothing else they will face in society will scare them anymore). For these reasons, many modern soldiers experience PTSD. In ancient times, PTSD was not so common (though it was just as bad - having to face your enemy and be literally knee deep in gore and feel his blood and guts on your hands and face - can be a scary thing to experience) because in addition to constantly facing war and death in the ancient world, soldiers also were psychologically trained to deal with fear. For example, in Ancient Sparta there was a "science" of fear that soldiers would pass on from generation to generation.

    [–]whuttupfoo 12 points13 points  (0 children)

    I already knew it was BS as soon as I read the post title.

    [–]kieran9323 2 points3 points  (0 children)

    same, even BBC news is low quality, with tabloid like topics plotted in, lack of resources section, explaining as if the reader left school at 16 - is that a target audience? If someone links to Huffington Post or similar ... it just tells me a lot about that person

    [–]jigglyp33n 1 point2 points  (0 children)

    Same - and I really appreciate OP's refutation.

    [–][deleted] 1 point2 points  (0 children)

    Right on! HuffPro is only credible "evidence" for femi-Nazis. I would just assume ask my Husky for his opinion

    [–]welshmin 0 points1 point  (0 children)

    Well gosh, here I was about to go change big chunks of my life based on a huffpo piece

    [–]WolfofAnarchy 213 points214 points  (24 children)

    OP OF THE POST THIS IS REGARDING HERE

    Hi, I wrote the other article you're referring to. Although there's absolutely nothing good about BPAs and the other 'substances' mentioned to be in your water, I see that I was too fast with concluding it lowers Testosterone.

    Thank you for applying your knowledge to this subreddit.

    I apologize for the misinformation.

    [–]2InvoluntarySickCunt[S] 65 points66 points  (15 children)

    Thank you for the integrity and intellectual honesty you've shown in this reply.

    Skimming papers and jumping to conclusions is all too easy, and any scientifically minded person who claims to never have done it is lying.

    I look forward to discussing the literature with you and others in the future.

    [–]WolfofAnarchy 15 points16 points  (0 children)

    You're welcome. Thanks for this post. Actual science deserves to be known.

    [–][deleted] 6 points7 points  (0 children)

    I think the takeaway here is that it's important to be informed and cautious. It wasn't too long ago that a lot of people died because we thought radioactive materials were fun (radium watches to glow in the dark for example). Learn how to interpret actual science so you don't fall prey to the media's view on it. A correlation that is barely beyond experimental uncertainty can be picked up and declared gospel while much stronger evidence is buried.

    [–]laere 1 point2 points  (0 children)

    Have you done any research into things like toothpaste, body washes, shampoo's, etc? I've heard of things like flouride in toothpaste and xenoestrogens (if that's a real word) in conditioners, body washes, shampoo's and some soap products. I am pretty skeptical about it, and I personally have done 0 research on it. I heard it off hand from a friend before finding TRP, and was curious if you've heard anything similiar?

    [–]LazyMagus 6 points7 points  (0 children)

    It requires tremendous confidence and humility to accept one's shortcomings like this in public. Good job, man.

    [–]Golderoy_Lickhart 7 points8 points  (0 children)

    the thing being good about BPAs is, is that they do not do the exact same things you imagined.

    there are plastics not being suited for consumable goods. people would use them if not for bpa.
    your apology is accepted though, because mistakes are human.

    [–][deleted]  (1 child)

    [removed]

      [–]2InvoluntarySickCunt[S] 1 point2 points  (0 children)

      For BPA, the lowest dose studied for risk assessment purposes was 50 mg/kg/day, which is the currently accepted lowest observed adverse effect level (LOAEL) that was used to calculate a reference dose of 50 μg/kg/day based on experiments conducted in the 1980s (IRIS 1988).

      BPA is often described as a very “weak” estrogen because in a few assay systems, such as MCF-7 breast cancer cells in culture, the dose of BPA required to stimulate cell proliferation (~ 10−7 M or 23 ppb) is roughly 100,000 times higher relative to estradiol, which stimulates cell proliferation at approximately 10−12 M (Welshons et al. 1999).

      The article goes on to say that at extremely low concentrations, (parts per trillion), BPA mimics estradiol in its ability to stimulate a calcium flux within MCF7 and rat pituitary tumor cell lines (calcium ions act as a signaling molecule within the cell through their interaction with calcium binding proteins, leading to non-binary signaling arrays). Anyway, this doesn't really have any bearing on my thesis, which is that macro-scale effects in humans don't seem plausible in the general population.

      [–]Endorsed ContributorJamesSkepp 79 points80 points  (13 children)

      We need more people like you here.

       

      The impact of "plastic" on T levels might as well be true (or might be not, science will tell sooner or later). So far there's enough evidence (despite rather simplistic conclusions b/c endoctrine system is a bit more complicated than "just measure T levels" as is the chemistry of "plastic" interactions with it) to warrant further research, which is being done.

      As I said in my reply to the first article - science will tell - and it did. This is why you trust scientists not opinion blogs, this is the difference between people who know stuff and people who have an opinion about stuff.

       

      Look at the model organism in the study. How close is it to human? In scale? Genetically? Is it cancerous? In these cases, rodent models would have been far superior to established cancer cell lines in my opinion.

      Read the results section first, the introduction second, and the methods last. Look at the figures, do they look right? Are they clear?

      Where is this info coming from? HuffPo? Or is it a legitimate scientific journal. Is it in all Chinese?

      Make sure that anyone who disagrees with your uninformed opinions is called a shill, as this argument has been passed down through the ages.

      You have no idea how funny that is for me when confronted with what certain user calls his own "method".

      [–]2InvoluntarySickCunt[S] 31 points32 points  (9 children)

      It's good to see that you and a few others represented voices of reason and skepticism in the original.

      [–]Kinbaku_enthusiast 11 points12 points  (7 children)

      I think it's healthy that people were skeptical. I think it's unhealthy that everybody bows down immediately to this OP, instead of applying a similar skepsis.

      There are definitely studies that show that BPA is a growing concern for its xenoestrogenic effect and ubiqutousness in our products:

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280330

      EDIT: it's valuable to look at this follow up post and judge for yourself: https://www.reddit.com/r/TheRedPill/comments/6yt1ak/no_plastics_are_not_lowering_your_testosterone/dmqb6ik/

      [–]2InvoluntarySickCunt[S] 11 points12 points  (6 children)

      You're absolutely right, and I appreciate you digging up more sources. This is an ongoing debate and will be on going for a while.

      [–]Senior Endorsed Contributormax_peenor 5 points6 points  (4 children)

      Meanwhile, is there any harm in avoiding drinking from things that smell like tires?

      [–]antariusz 2 points3 points  (3 children)

      Nope, other than losing out on the convenience factor, you might be inconveniencing yourself over things that aren't actually impacting your life.

      For example, the people who move away from high power lines or refuse to use cell-phones because of "the radiation". Or that don't vaccinate their kids because of "toxins"

      That being said, where I work, we went from handling literally thousands of pages of thermal printed pages of information a day down to about half a sheet worth of information.... and I'm much much happier about it. Thank god for technological progress.

      [–]Senior Endorsed Contributormax_peenor 1 point2 points  (2 children)

      other than losing out on the convenience factor

      Drink from something that smells like tires is convenient? Do you cruise HB3s at the club because they are easy to ride?

      [–]antariusz 1 point2 points  (1 child)

      Sure, and someone else will say if you don't wash your hands for 45 seconds (but not 44 or 46) and then flick the bathroom light 5 times something bad will happen to you too, but I prefer not to be crazy (in the classical sense of the word).

      There is convenience in being sane. I spend my mental energy on many other things, my water bottle is not one of them. Making sure I'm not fucking a 3/10 happens to be one of the things I spend far more time thinking about... than the plastic a water bottle is made from.

      Actual issues that affect your life will always take precedent over things that neither affect my life, nor that I can have any effect on.

      For example, Im 5'8" and if I spent all my time worrying about being short, that would be wasted energy. Because A) I'm not that short, and B) I can't do anything about it, except I generally wear boots because it's nice to be average. C) The reason I'm not getting laid (theoretically speaking, because I currently have no problem in that department) is not my height.

      In the old days, pre-internet, they called people like that penny-wise but pound-foolish. Don't be that. Spend an appropriate amount of time on each problem as is appropriate for not only its severity, but also your ability to fix it.

      Something that theoretically might or might not impact my testosterone/estrogen level, by a tiny theoretical percentage, I don't care about.

      My ability to easily have access to water for hormone production (ever take a glass into a car?) outweighs the possible downsides of hormone production from what the water bottle is made of.

      [–]Senior Endorsed Contributormax_peenor 0 points1 point  (0 children)

      There is convenience in being sane.

      Choosing quality over shit is sane. I have a choice of two products that DO the same thing; I'll pick the one that doesn't smell funny. This is an actual issue that affects my life, ever single time I take a sip. I don't need someone to go on a rant about science to tell me this.

      [–]hexagonsol 0 points1 point  (0 children)

      Hey, fellow researcher here, want to get in a discord next sunday and go through the literature?

      [–]tb87670 3 points4 points  (1 child)

      We need more people like you here.

      Can't say that enough. The bro-science I have seen in my few years hanging around TRP in posts and private messages has made me concerned.

      "Don't whack off and lift bro, you reduce your gains"

      "No-FAP for months, you get to keep your test levels up man"

      "Do an exercise a certain way to tone them muscles even more with the same effort, brotastic"

      "Lots of anti-oxidants are good for you, especially if you weight lift bro"

      [–]Senior Endorsed ContributorRian_Stone 2 points3 points  (0 children)

      I thought you were an automated script, not a shill

      [–]Kinbaku_enthusiast 15 points16 points  (4 children)

      Why you should trust my judgement: I am a molecular biologist and immunologist who is active in the academic sphere and have expertise in in vitro cellular assays. This is a fancy way of saying that I grow lots of cells in plastic dishes and then look at them in different ways, and it's how most of these studies are conducted. Also, it's my job to evaluate academic literature.

      How do we know that you are?

      Now keep in mind that polymer chemistry is really a black magic in itself

      So it's hard to judge for certain in either direction?

      Think about it, if plastics were a government conspiracy like some of you apparently think, why would they use them on their own fucking armed forces?!

      There may be any number of explanations for this, from being an acceptable cost for another goal to minimizing BPA exposure for armed forces.


      I want to take your post at face value, I really do. Particularly since I am neither a chemist or educated in reviewing scientific literature.

      While recognizing my own lack of scientific training, I have come across multiple instances where people try to claim authority and bludgeon away an idea, not atypically with a strong trust in the state, despite history being rife with examples where conspiracies against the public did take place, such as the mk-ultra experiments where unsuspecting civilians were fed LSD for months to discover its coercive effects, for example. This was long one of those kooky conspiracy theories, until the CIA unveiled documents that say it did happen.

      let's get into some specifics

      Regardless of your position in regards to plastics as a whole, I did come across studies in my country that the sludge water, the mix of mud and water on shores of our rivers (netherlands), had high estrogenic qualities. Our water supply itself did not have these high levels, but according to the paper we neither routinely tested it or treated it to prevent it. I'll see if I can dig up the study.

      The following article, much like the supposed test subject that posted in the previous post, show that it is practically impossible to currently avoid getting BPA into your system.

      http://www.sciencedirect.com/science/article/pii/S0960076011001063

      There are studies that support the adverse effect on testosterone production by BPA:

      http://www.sciencedirect.com/science/article/pii/S0378427410000561 https://academic.oup.com/endo/article/149/3/988/2454992/Bisphenol-A-Prevents-the-Synaptogenic-Response-to

      And this older study from 2005 gives a roundup of previous literature:

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280330/

      For someone preaching skepticism, your mind does seem to be made up (judging from your title), when from my perspective there seems to be more than ample evidence that it's likely though not certain BPA messes with our testosterone production.

      Of course it took decades to conclusively prove the dangers of smoking too. It seems to me there is far too much evidence currently out to simply dismiss the xeno-estrogenic effects of BPA, which is in most plastics (and unfortunately seem impossible to avoid wholly).

      [–]2InvoluntarySickCunt[S] 3 points4 points  (2 children)

      Thank you for citing your sources I will take a look after work. Please note that I am NOT claiming that plasticizers do not have the capability to do harm in vivo. I am claimimg that ths original evidence presented was insufficient to support thay claim. This is why the thesis of my post is essentially, "show me the data". My post was more concerned with scientific skepticism and intellectual honesty than this issue in particular.

      Thanks for your thoughtful input friend.

      Edit: Ok let's take a look at your linked studies.

      Starting w/ "Bisphenol A Prevents the Synaptogenic Response to Testosterone in the Brain of Adult Male Rats". The article culminates in the claim that:

      bisphenol A prevented both the prefrontal and hippocampal synaptogenic response to testosterone supplementation in castrated males

      This basically means that, at a BPA dose of 300ug/kg, or around 21 mg or an average adult male, supplemental testosterone (in the form of testosterone propionate @ 1.5mg/kg) had impaired binding in 2 specific brain regions. While this is interesting, testosterone isn't actually decreasing, it's undergoing competitive inhibition in these specific cells in this specific model at this specific dose, which is quite high. While this kind of paper warrants further investigation at far, FAR lower doses, I don't see cause for concern to the average consumer.

      I'll do the other primary one because a review article doesn't really have much to refute, its just a conglomeration of other primary literature: "Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol"

      Prepubertal Wistar/ST male rats (4 weeks old) were subcutaneously administered BPA (0, 20, 100 and 200 mg/kg/day) or E2 (10 and 100 μg/kg/day) for 6 weeks. Both BPA and E2 treatments decreased plasma and testicular testosterone levels, and plasma luteinizing hormone (LH), but not E2 and follicle-stimulating hormone levels...

      Ok, so in this case the dosage of BPA they're administering is fucking insane. Also note that prepubertal rats were used. I would argue that puberty changes brain chemistry significantly but anyways, Average test in males is between 280-1,100 nanograms per dL or 10 liters of blood (average adult male blood volume is 5.5 L). If we do the math real quick we can see that they're administering roughly (200 mg/kg body mass * avg adult weight of ~70kg) / 1.1x10-6 g = 12,727 times the amount of testosterone in an extremely high test individual of BPA PER DAY. For six weeks.

      I hope that this information convinces you as I can see you are quite the skeptic. Every study I have seen has used massive doses of these chemicals directly injected (not ingested).

      If you are convinced I would request that you please modify your other replies so as to not push studies making conclusions that their methodologies do not warrant.

      [–]Kinbaku_enthusiast 3 points4 points  (1 child)

      This is why the thesis of my post is essentially, "show me the data"

      The title you chose would suggest otherwise.

      Though I find overstated clickbaity titles conducive to getting people engaged (contrary to what intuition might suggest), so I'm not really faulting you for that and this response at least seems to show you're both serious and curious.

      I'm looking forward what you think about this after you've dug into it a little.

      I myself must confess that I did not engage with the sources of the previous post, since I had already come across a number of reasons to suspect BPA as a xeno-estrogen and having significant effects in vivo.


      Edit: for people reading keep in mind that this post was made prior to his edit.

      reply to edit:

      Thank you for the response. Your edit made my reply look asinine, but that's okay. I am grateful that you took the time to look into it seriously. I don't have the time to evaluate the veracity of your claims this weekend, but I will after it and regardless, the way you have presented information this time, I would consider it very likely that your assessment is correct.

      As a result, I've added in a link to your comment in my other skeptical replies.

      You might still be wrong in considering it safe, I don't know, but I consider it highly unlikely at this point. We'll see what I think after I've read the studies more closely, which probably goes slower for me, because as I've said before, I'm just a skeptical layman. We'll see.

      Thank you for engaging with this seriously and thank you for sharing your thoughts.

      [–]2InvoluntarySickCunt[S] 1 point2 points  (0 children)

      Please see above.

      [–]BullshittingNonsense 1 point2 points  (0 children)

      After MKUltra, it's absurd more wasn't done to reign in the intelligence agencies

      [–]WISE_TURD 9 points10 points  (2 children)

      I don't doubt the legitimacy of your argument; I see it as risk/reward of two options (the worst case for each option):

      1. Avoiding plastics when they turn out to be benign, Cost: expended needless money and effort.

      2. Using plastics when they turn out to be harmful, Cost: my physical well-being, the extent of which is unknown.

      It's an ongoing cost/benefit analysis: -If i'm in a setting (hospital) where plastics are predominantly used, i won't complain about their use. -If I have the choice of not using plastic at a marginally higher cost, i'll likely choose no plastic (getting a glass or stainless steel water bottle instead of plastic or using foil instead of saran wrap).

      -If plastics are harmful, we'll likely find out when it's too late.

      -Avoiding plastics when you can is prudent. Completely abstaining from all polymers is as futile as it is time-consuming.

      [–]RedSugarPill 1 point2 points  (0 children)

      You the real RP! Precisely spoken

      [–]1SuperStalin 27 points28 points  (14 children)

      whatever chemical we use lowers testosterone leves - it's not nearly as detrimental as behaviours which lower testosterone levels

      [–]185poundsofhatredWIP 4 points5 points  (10 children)

      What behavior lowers testosterone?

      [–]1SuperStalin 24 points25 points  (6 children)

      being complacent, inactive, indecisive, passive... when you don't use your testosterone production facilities AKA balls

      [–]1PantsonFire1234 4 points5 points  (0 children)

      Exactly, some things might tamper my levels but compared to the rest of the population it's obvious i'm not missing out. Drinking alcohol for example. If you party like a raging whore every weekend you are only achieving three things. 1. a drain on your bank account 2. lots of fake numbers and those that go nowhere 3. muscle loss, T loss, loss of healthy appetite.

      Maybe sometimes you get laid. Probably less and less so after you poisoned yourself enough. Things like that impact you far more than a plastic bottle.

      [–]185poundsofhatredWIP 5 points6 points  (2 children)

      Do you have any studies that back this up?

      [–]1SuperStalin 3 points4 points  (1 child)

      Actually I did read some studies about how european football fans have raised testosterone levels from just being a part of a group of males... but I can't be arsed to search on my phone.

      Also, lifting heavy weights, especially squats co-relates positively with long term T-level raise.

      [–]George_Rockwell 0 points1 point  (0 children)

      This is actually very interesting. Someone post links damnit

      [–]donkey_democrat 2 points3 points  (1 child)

      Isn't it a chicken and egg type situation?

      [–]1SuperStalin 1 point2 points  (0 children)

      It's not if you live in a family or a wider society where being a man is frowned upon.

      Ask men who've grown up without a male role model

      [–]1mental_models 2 points3 points  (2 children)

      deference, bad posture, lack of mindfulness (getting emotionally overwhelmed and stressed-out /cortisol), lack of eating/supplementing right, lack of talking to attractive women, lack of ever being the alpha in any social situations,

      [–]185poundsofhatredWIP 0 points1 point  (1 child)

      Do you have any studies that back this up?

      [–]1mental_models 0 points1 point  (0 children)

      some of these are common knowledge and some have studies.

      google "Proceedings of the Royal Society B" with "testosterone" until you find a univ cal study. - that will show you one study. Sorry don't have time to present it like a term paper or scientific study at the moment. Good luck.

      [–]2InvoluntarySickCunt[S] 2 points3 points  (0 children)

      I think this post has tremendous value and of I could sticky it I would. Thanks for the input and I hope everyone takes the time to do some research on prolonged sitting, posture, cortisol, exercise, and T levels.

      [–]LOST_TALE 1 point2 points  (0 children)

      like losing.

      I listened to a secondary source that losing or winning in competition affects your testosterone levels

      [–]KlM-J0NG-UN 13 points14 points  (1 child)

      What about the gay frogs doe

      [–][deleted] 17 points18 points  (5 children)

      Nice

      Filtered water in my plastic PUR filter won't make me buy an Xbox.

      Ta mate. +1 Internets.

      [–]AlphaGrad 2 points3 points  (0 children)

      That's cuz we all know PC is better than consoles.

      [–]2InvoluntarySickCunt[S] 4 points5 points  (3 children)

      If mind control were that simple I'd think academics could find a way to make more money!

      [–]sorceryofthetesticle 8 points9 points  (2 children)

      Wrong again! The real academics work for Tampon Corp and have convinced the beta labrat underling workforce to wear testosterone shredding nitrile gloves. Might as well change your name to InvoluntarySickCuck bro, sorry.

      [–]2InvoluntarySickCunt[S] 8 points9 points  (0 children)

      Damn I knew those gloves were pink for a reason. It was right in front of my eyes the whole time!

      [–]Endorsed ContributorMentORPHEUS 6 points7 points  (3 children)

      I'm not really a fan of this essay. It purports to be scientific, but is written in a flippant manner typical of anti-science writers. It spends a long time being dismissive of a few claimed sources of estrogen-mimics, but apparently ignores the reality that humans bear a heavy load of not only this class of chemicals, but PCBs, furans, PFOA, phthalates, organochlorate/phosphates, and VOCs.

      "That New Car Smell" is largely plasticizers. Cheap plastic car mats positively reek of phthalate, so do many cheap imported plastic products.

      This may diminish the claims made in particular articles from the other post, but it doesn't make a good case to dismiss one's concerns about body chemical burdens entirely.

      [–]2InvoluntarySickCunt[S] 1 point2 points  (2 children)

      I believe that, as GLO mentioned in his front page post earlier today, the key to having an informative and impactful post is to match the style to the audience. You're absolutely correct that the post is flippant; i wrote it that way by design to gain the attention of the young men who make up the audience. From my perspective, getting people thinking critically is the ultimate goal.

      In the comments below I've picked through several other studies on BPA specifically to demonstrate how oftentimes in research, the conclusions of the authors are contradicted by their methodology. Not all peer-reviews are equal, as it were.

      Anyway, criticisms of my style aside, the point I'm trying to make was never about any material in specific. The point was that people need to read the literature that they're purporting to understand, because the truth is nuanced.

      [–]Endorsed ContributorMentORPHEUS 4 points5 points  (1 child)

      the key to having an informative and impactful post is to match the style to the audience

      That's not wrong, but a writer can't neglect matching the style to the gravitas of the subject matter as well. This was well suited for debunking a 100% false claim, and then to an audience that already mostly agrees. For this particular topic, where there remains an underlying serious concern, and to a broad audience, talking about scientific matters in the typical manner of anti-science writers results in cognitive dissonance. Is he being dismissive of those who stretch and fabricate scientific facts, or science itself?

      Anyway, that's my feedback on this particular post. I'll look with interest for further writings of yours.

      [–]2InvoluntarySickCunt[S] 2 points3 points  (0 children)

      I thank you sincerely for the thoughtful feedback. I hadn't considered that perspective and was writing hastily right before bed; I got a bit lazy. I still think my criticisms of the original articles stand for themselves despite the tone- but again- thank you.

      This kind of dialogue is what makes this community unique.

      [–]ytfromsnwcrsh 8 points9 points  (4 children)

      To whom may be interested in Testosterone levels, here are some tips that can save you time and point you in the right direction if you want to research and act on your problem. My testosterone levels were in the low threshold, dont know how is measured in america by in my country my level was 290. I was suffering from various methabolic disorders, high blood pressure, high sugar in the blood, was 20kg overweight and had tits bigger than my girl`s. Now, 14 months later, my T level is 730, my workout at the gym actually makes visible difference in terms of muscle. lost those 20kgs and my blood tests and exams are normal again. What is the trick? I cut carbs and sugar (not radically, but I only eat that poison exceptionally). I went to endochrinologist doctor with all my research and showed him, and said I would do that with or without medical supervision. He jumped in and bought the idea, skeptical at first but he finally admitted I had a point, after my new blood tests. Ok, testosterone replenishment per si can make your body stop producing it. The way I found to get around this was a new treatment. The drug XXXX(please google and find out) (commercial names are xxxx or xxxx, in my country). It is a drug used to induce ovulation in women that cannot get pregnant. Fertility Doctors also prescribed it off label to the husbands to increase sperm production and ejaculation volume. It triggers your own body to produce testosterone. It worked for me, I had one of those pills every day and now Doctor reduce to one every two days, to keep my testosterone under 800. The sperm volume actually increased (but I didnt have problems there before) and my testies did not shrink, on the contrary, they seem fuller. In most aspects I feel like I am 29 again (Im 44 years old), not miracle overnight but definitely worth taking a look if you are in the situation I was. EDIT: removed the drug name and commercial brands, its not rocket science to find the names on line. Or PM me if you need.

      [–]factus10 11 points12 points  (0 children)

      This: obesity is responsible for your lower testosterone levels.

      http://www.buffalo.edu/news/releases/2010/05/11311.html

      [–]Fedor_Gavnyukov 5 points6 points  (2 children)

      the drug is called clomid for anyone wondering. it may or may not work for everyone. the tests needed to be performed to see if clomid might actually work are for primary and secondary hypogonadism. your LH and FSH levels should tell you a great deal about it.

      [–]un-supervised-savage 0 points1 point  (1 child)

      There are a few others that work better than clomid. Clomid is a fairly old drug but still does the trick.

      [–]D3ATH94 4 points5 points  (1 child)

      Thank you for confirming my theory that quite a few Red Pillers are gullible idiots so long as a post is formatted well and matches their view points.

      [–]Dead__Hand 4 points5 points  (1 child)

      You provide some excellent reasons to be skeptical.

      However, we are still faced with the fact that sperm counts in western men have dropped by something like 50% in the last 50 years. Now, it is a jump from there to saying that a decrease in testosterone is playing an important role, but assuming that is the case (and I acknowledge that, if this is wrong, the rest does not follow): we need to account for what is lowering population testosterone levels.

      Plastics and other endocrine disrupters (e.g. soy) interfering with T levels seems like a plausible explanation (at least in part).

      The thing about reasoning is that we don't actually proceed inductively or deductively in our every day life - not really. Most of our reasoning is "abductive" - also known as "inference to the best explanation". It's a weaker form of inference than induction (inference from the particular to the general, e.g. scientific generalizations) and deduction (necessary inference built up from first principles, e.g. math). But it's still a legitimate one.

      At this time, environmental plastics playing a role in lowering testosterone levels seems to me to be (part of) the best available explanation for lower testosterone levels.

      [–]BaronVonNrx 2 points3 points  (0 children)

      The problem is that is that society as directed(by media, academia, corporations etc) has apparently no desire to find a solution for lowering sperm counts and lowered testosterone in western men.

      It is not much of a leap to conclude that it's intentional. (As demographic displacement of the founding stock of western countries by third world immigrants is an obvious objective) as is creating a more docile male population.

      There is a massive demand within the male community for increased testosterone so no one can tell me this is just based on free market demand.

      So we are stuck grasping at straws as to how to counteract the apparent assault on what makes us men.

      [–]Roetenin 2 points3 points  (0 children)

      Thanks for the insight. However I'm curious about heating/cooking food stuffs in certain plastic containers/packaging. Would this have more of an impact in any way?

      [–]Shaman6624 2 points3 points  (0 children)

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210908/ you say a few picogram but this study suggests it's a lot more.

      [–]Senior Contributor: "The Court Jester"GayLubeOil 17 points18 points  (6 children)

      Can you stay? We need you. Stay and help us wrangle our sperg children. Help them develop critical reading skills their teachers never taught them.

      [–]jonknownothing 43 points44 points  (5 children)

      dude, you were agreeing with the other article before. Stop acting like wise old man

      [–]anonymoushero1 3 points4 points  (1 child)

      its fucking sad that you need to go these lengths to try to explain to people that retards online aren't to be taken seriously.

      [–]1PantsonFire1234 2 points3 points  (0 children)

      Granted, certified government officials, social workers and licences politicians are not to be taken serious either. So where does a man turn to when he is out of his field of expertise? Exactly, to another rationale man who is in this field. Like OP.

      In essence that's what the red pill is all about. Not taking information from anyone but from the accumulative as a whole and deciding which information holds truth.

      [–]2IVIaskerade 1 point2 points  (4 children)

      Questions:

      Do you think that BPAs (less so nowadays) and phthalate-based plasticisers do not have xenoestrogenic properties?

      Do you think that there hasn't been a marked rise in estrogen levels in water sources due to female contraception?

      [–]2InvoluntarySickCunt[S] 2 points3 points  (3 children)

      The evidence is clear that some plasticizer compounds do indeed exhibit xenoestrogenic properties, at least in vitro. Where i become skeptical is claims of macro-scale physiological effects in the general population as a result of those compounds use in consumer goods.

      What's most important to note is the concentrations at which effects begin to manifest, and the specifics of those effects. For instance, how does the binding affinity of estrogen-mimicking compounds to the androgen receptor compare to actual estrogen? Are these molecules polar or nonpolar? Hormones typically act on transcription factors in the nucleus and can pass through membranes easily.

      I always say, in in vitro experiments you can shoot a cell dish and then claim it was the lead in the bullet that killed the cells.

      Great question.

      As for BC contributing, I'm not familiar with the literature. Let me do some research tomorrow and I'll message you privately with my opinion. If I had to guess I would say it would be measurable increase but physiologically negligible since so much BC has become progesterone based or implantable. Could be wrong here though.

      [–]Senior Endorsed Contributormax_peenor 0 points1 point  (2 children)

      The evidence is clear that some plasticizer compounds do indeed exhibit xenoestrogenic properties, at least in vitro. Where i become skeptical is claims of macro-scale physiological effects in the general population as a result of those compounds use in consumer goods.

      See, this is where I have a problem with your post. When people throw fits about mercury in their flu shots, it's fucking retarded. When you look at the available science there is no serious reason to worry about it, but there is definite reasons why the flu vaccine has huge health benefits, which in many cases are life saving. What we are talking about here is the quality of food containers. There are tons of choices in this department AND there are some indications that the containers in question might be a problem. The only reason these in question exist is because it is cheaper for the manufacturers to make.

      So why am I choosing a potential problem just to make someone else some more profit? When you play science all the time you lose the big picture and that's what happened here.

      You'll notice my response in the previous thread was about how LCF reacted. It was an overreaction and she will admit it. However, the stuff we have now is much higher quality and the cost is not an issue for me. In the big picture, the overreaction was a net positive to me.

      [–]2InvoluntarySickCunt[S] 0 points1 point  (1 child)

      I understand and respect your viewpoint but I feel I must clarify- I'm simply stating that I have not seen sufficient evidence of a effect on the human level. If evidence is provided I am ready to modify my post and torch some university buildings.

      We can debate the ethics of companies saving a buck at the potential cost of consumer health and how the free market and general education can combat this, but I feel that that discussion belongs in a different post.

      [–]Senior Endorsed Contributormax_peenor 0 points1 point  (0 children)

      I have not seen sufficient evidence

      Arbitrary metric, but here's the point: if there was a mountain of evidence or no evidence, then the course of action would be obvious. However, if there is some evidence, then the course of action needs to be a discussion of risk. You cannot separate these things. You want a real world example of why this is? Medical science. Its practice is almost entirely balancing what we know, which is almost never everything, against what we know about the risks. Now I will admit given what we know here, the risks would appear to be ridiculously low.

      [–]michael_wilkins 1 point2 points  (1 child)

      Since there always has to be one cheeky cunt in every thread like this I'll do it and g et it out of the way so no-one else has too:

      and illustrates the need for a quick run-down of scientific skepticism.

      Ok

      Why you should trust my judgement: I am a molecular biologist and immunologist who is active in the academic sphere and have expertise in in vitro cellular assays.

      Appear to authority fallacy.

      But in all seriousness I do have a couple of questions regarding plastics.

      I've been lead to believe that plastics are harmful to animals because they are essentially unable to be broken down, the fragments of plastic just get divided into smaller and smaller pieces and hang around in the bodies of animals that ingest them, moving up the food chain.

      I presume that the human digestive system has no method of digesting plastic, so similar to fibre and other indigestible molecules it just gets passed.

      I believe this is where most of the "danger" from plastic comes from, when particles are small enough to pass through the digestive system into the rest of the body through diffusion because of their small size. Presumably they are not recognised as a pathogen so they just sit there, accumulating.

      So my concern is that is there nothing the body that can break down plastic completely? not even stomach acid? an immune response? If there isn't, what does the plastic do in the body?

      An EC should award a point for OP as well.

      [–]2InvoluntarySickCunt[S] 3 points4 points  (0 children)

      Why you should trust my judgement: I am a molecular biologist and immunologist who is active in the academic sphere and have expertise in in vitro cellular assays.

      Appear to authority fallacy.

      Yes!!! I was hoping someone would call me on this! Naturally I cannot provide detailed evidence of my stature in the academic realm due to the political climate and the forum on which we are debating.

      I implore every reader to trust my arguments on those arguments' merits alone.

      I'll respond to the other remarks in this post later as an edit.

      [–]joh2141 1 point2 points  (0 children)

      At the end of the day most people don't read or research or find sources so even if you warn them and people go "I UNDERSTAND OP, I WILL HEED YOUR WORDS TILL THE DAY I DIE," they'll forget it tomorrow. Huff Puff sucks period but never forget to question and never take anything at face value. Most scientific research will publicly release their experiment/data. You can review it yourself and see whether the data is compromised or concrete or still remains to be conclusive. Federal agencies like CDC is still trustworthy. It's just CIA and NSA that people don't like.

      [–][deleted] 1 point2 points  (1 child)

      how can we be sure you're not some paid shill employed by Big Tampon?

      [–]1PantsonFire1234 1 point2 points  (0 children)

      Always possible, that's why you need to fact check what OP says. Some of us are to busy, hence why we need a critical user base. Couple guys find the time to do this before the end of the weekend. One guy rings the bell and calls out OP on his bullshit. People not allocate their own time to verify and the post gets labelled bs.

      The problem now is that everyone just blindly agrees. The first post everyone agreed. Now everyone agrees again. It's the easiest way. Also I really doubt everyone who read the post is swamped this weekend. Especially the EC's and mods who are partially responsible for the quality on this sub.

      That or just look at OP's commenting history and decide if he's legit.

      [–]Senior Endorsed ContributorRian_Stone 1 point2 points  (0 children)

      Like I said last thread. My whiskey hobby affects it far more than BPA does.

      low hanging fruit

      [–]RotmgCamel 1 point2 points  (0 children)

      I just skim read the post. This reminds me of one of my favourite stoicism quotes that has stuck in my head.

      We are too much accustomed to attribute to a single cause that which is the product of several, and the majority of our controversies come from that. - Marcus Aurelius

      People will get uppity about all sorts of things but I'll say testosterone seems to be affected ~90% by Porn+diet+exercise.

      Any other factors like plastics or radio waves or radiation which may have some sort of effect on the body, make very little impact in comparison to these others.

      But people use these tiny reasons as excuses so they can hide from the big things.

      [–]adr007 4 points5 points  (0 children)

      Fellow molecular biologist, I salute the work you've done here.

      [–][deleted] 2 points3 points  (4 children)

      I really hated that initial post acting like plastic water bottles would turn you into a sniveling soyboy (although you can bet your ass that heated greasy food in a plastic container will confer noticeable and measurable estrogenic activity... I, ahem, had a short bout of gyno which was extremely responsive to anything estrogenic, and those suckers stung and doubled in size within an hour of eating lasagna heated up in a cheap plastic sandwich tupperware). I didn't have the time, energy, nor wherewithal to debate it but you, sir, have common sensed/scienced his ass more effectively than I could have though, so kudos for the quality post.

      [–]un-supervised-savage 0 points1 point  (3 children)

      The problem is some guys are more sensitive to estrogen than others. So they will write it off as anecdotal evidence because it didn't work for them or it wasn't reproduced in a peer review study. Making personal changes and monitoring your own blood work to see how those changes work for you is the best way to go about it. Going with non bpa plastic/metal bottles for water and definitely avoiding heated plastics contact with my food/water the best I can have personally made my nipples less puffy/sensitive. On top of keeping very lean.

      [–][deleted] 0 points1 point  (2 children)

      I think that's definitely true, but some guys are also not very perceptive or critical when it comes to the effects of things they're eating. My gyno was reversed with tamoxifen and avoiding estrogenic foods, but when I had it, it was very clear which foods were making it worse by binding to those estrogen receptors. Soy, cheap refined fat foods with no fiber (which probably had an indirect effect on endogenous estrogen), too much stone fruit, and plastic were all extremely clear culprits when it came to estrogenic activity.

      Actually, the OP's post is slightly misleading since you have to kind of make inferences when it comes to scientific understanding, rather than just reading the results of a few limited, lackluster studies with weak methodology. This is actually a very difficult subject to study for many reasons and we are far from understanding the effects of plastics on the body. We barely even understand what phytoestrogen ligands do in the body aside from loosely correlating them with lowered testosterone and lowered hormone receptor positive cancer risk, which some studies conflict with as well. Nutrition science is a weak area of science to be sure.

      [–]un-supervised-savage 0 points1 point  (1 child)

      I definitely agree that there needs to be more scientific studies done in the nutrition field. You pretty much have to test them all out yourself to see what works. Then look for the available science there is on it to get a loose understanding of why it worked. I've been playing with different diets for most of my life and still haven't mastered what works best for me. I'd went with some consulting from a top level nutritionist that specializes in preping pro competitors and learned more in 12 weeks than the past 18 years. Folks like that don't drop that info into the internet hoping to teach the masses because there's limited controlled studies on it, and why give away tips for free when you can make money from it by reputation.

      [–][deleted] 0 points1 point  (0 children)

      Same here. I've been experimenting and poring over nutrition science studies on a near constant basis since I first got into bodybuilding, and especially when I hit my early 20's and had some health issues. At first, I didn't even understand the value of fiber aside from colon health. Now I recognize that fiber is not only crucial for the health of every tissue in the body, but that every source of fiber has essentially its own unique effects (not to mention the thousands of accompanying phytonutrients with unique effects). It's immense, yet I feel like having that foundation of nutrition science sets you up for future success. I constantly feel sharper and lighter as I continue to increase my Omega 3 ratio, etc. And yet doctors know very little about nutrition, and nutritionists often pick a side and only share the evidence that supports it (e.g. Dr. Gregor of NutritionFacts.org, who selectively shares only studies that support a vegan diet - and he himself looks like a pale bag of bones). Essentially, it's entirely up to us, with the help of experts and science, to forge our own sense of nutritional understanding because nothing can help promote our own understanding quite as well as personal experience and a bevy of complex, contradictory knowledge.

      [–]Golderoy_Lickhart 0 points1 point  (0 children)

      i salute you for bringing real quality content back. like, science for once and for all.

      [–]Disciple_of_Libertas 0 points1 point  (4 children)

      Interesting, I'm still not a huge fan of plastics. I am.inerested in hearing your opinion on what may be the source of decreasing test levels in Western men.

      [–]1PantsonFire1234 2 points3 points  (2 children)

      • No exercise (no real excersise)
      • No confidence (power stances, body language)
      • Feminine behaviors and emotional sophilism
      • Crap diet
      • Alcohol, smoking, drugs
      • Genetics (bad breeding)
      • Lack of sun (hello upper northern hemisphere)
      • Stress, Depression, Cognitive Dissonance, Mental illnesses

      Honestly there's more but you get the point. Everything contributes to it. Women btw are also low E just like men are low T. Attributing everything to guys and pretending like women don't suck is the highest of fallacy's

      [–]Kinbaku_enthusiast 0 points1 point  (1 child)

      Women btw are also low E

      Based on what? It's more likely that they're too high in E, as they too are vulnerable to the xeno-estrogens.

      On top of that, many are on the pill, which frequently has estrogen in it.

      [–]1PantsonFire1234 1 point2 points  (0 children)

      I'm not sure about the science behind it all but it's a repeated sentiment among those who look at society making red pill observations. Broad shouldered hambeasts for example. Thick girls etc. Men need allot of T to get the engine starting, a little bit of T is enough to fuck with a woman's hormones though. You won't see chicks growing beards but the imbalance created by a shitty diet (McDonalds) and binge drinking is enough to change a sensual woman. Same can be said for men, the T-lowering factors just bottles down to hormonal imbalance. So you won't be growing tits but certainly won't be Chad either.

      [–]un-supervised-savage 2 points3 points  (0 children)

      Sedentary lifestyle is a large irrefutable factor.

      [–]notajith 0 points1 point  (0 children)

      What about chlorinated PVC? In my area CPVC can be used for household water supply. PEX is also available but is unpopular for anything but new construction.

      [–]TheBloodEagleX 0 points1 point  (0 children)

      [–]factus10 0 points1 point  (0 children)

      Concerned about your testosterone levels? Lose weight.

      http://www.buffalo.edu/news/releases/2010/05/11311.html

      [–]do_it_or_leave 0 points1 point  (0 children)

      We need more people like you.

      Do you have something to say about deodorants with aluminum?

      [–]We_Flatten_Stuff 0 points1 point  (0 children)

      I think you're just Big plastics trying to trick us /s
      Nice to see a well written comprehensive post, that was interesting thanks

      [–]reddttt 0 points1 point  (1 child)

      How can you like biomolecules that much. Holy fuck that shit brings painful memories from a past semester in my current medschool. That shit is fucking boring.

      [–]BiggestBoop 0 points1 point  (0 children)

      Thank you for this! There are far too many posts here with anti-science undertones. Or even explicitly anti-science ones like you just mentioned.

      [–]omega_dawg93 0 points1 point  (1 child)

      dude said, "weekly prostate exams." lol.

      [–]2InvoluntarySickCunt[S] 1 point2 points  (0 children)

      Want to help make it daily?

      [–]Senior Endorsed Contributormax_peenor 0 points1 point  (0 children)

      The Mysterious Case of Shitty Workers' Rights in China

      Completely unrelated to your post, kinda, but I do have a problem here. We debate the dangers of properly manufactured products, but we get container ships full of poorly manufactured garbage from China all the time. How many houses have had their drywall and/or flooring ripped out in the last couple years because it was slowly killing the residents? More than one. So keep that in mind. Even if you are convinced the alleged material is safe, who the hell knows if you are actually getting that if you are buying low quality cheap shit.

      [–]Putins_Masseuse 0 points1 point  (0 children)

      I wonder who's downvoting this

      [–]thInc 0 points1 point  (0 children)

      I'm more concerned about eating fish due to bioaccumulation and the ocean food chain. Can you comment on that issue?

      [–]casemodsalt 0 points1 point  (0 children)

      I think masterbating while high on meth is what lowered mine.

      [–]TheSlicemanCometh 0 points1 point  (5 children)

      Okay, so what is the cause of the lowered testosterone in the west?

      [–]RedSugarPill 1 point2 points  (4 children)

      Not enough exercise can likely explain the effect

      [–]TheSlicemanCometh 0 points1 point  (3 children)

      That really explains the entire drop?

      [–]RedSugarPill 0 points1 point  (2 children)

      You can test it yourself. Check your t-levels now, then lift weights for a month and check again. You'll be amazed at the changes. Not just testosterone: quality of life is enhanced in many ways.

      [–]TheSlicemanCometh 0 points1 point  (1 child)

      1. That wouldnt measure shit on me considering Ive been lifting for the last month.

      2. The fact that lifting raises T doesnt mean drop in T is only due to lack of lifting.

      Do you have any evidence that people workout 50% less now than 20 years ago?

      [–]RedSugarPill 0 points1 point  (0 children)

      The evidence is my own body. I was trying to encourage you to do your own experiment. Since you're already healthy, you don't need my advice. The rest is just ego children scratch. All the best

      [–]kikage 0 points1 point  (0 children)

      If I wear a nitrile glove most of my day, should I be worried?

      [–]donkey_democrat 0 points1 point  (0 children)

      What about pesticides? The xenoestrogens present in society are not restricted to just plastics.

      [–]Chikinhok 0 points1 point  (0 children)

      What about flouride making us stupid? Know anything about that?

      [–]JFMX1996 0 points1 point  (0 children)

      While the BPA thing is controversial, it'd be cool to go more into environmental estrogens affecting young men later down the road.

      I think it is a topic that should be covered, as it could have a greater significance to why young men may be becoming more effeminate or lacking in masculine qualities.

      Things like all the estrogens in milk, tap water, etc.

      As well as dietary influences on our endocrine systems.

      [–]Iconoclast674 0 points1 point  (5 children)

      Triclosan in many antibacterial soaps, like Dial, has only recently been regulated by the FDA.

      This chemical is a hormone disruption, and can mimic estrogen in the body.

      [–]latincanuck 0 points1 point  (4 children)

      No they are reviewing it still, it is considered an emerging concern, and it banned the marketing of antibacterial soap and mouthwash, as these were not proven to be any more beneficial than using regular soap. As well the fda did not say triclosan is a hormone disruptor but is possibly harmful to the environment. in the ban that the FDA was talking about there were 19 chemicals named, some of them or one of them may be a hormonal disruptor This is the type of fear mongering he is talking about.

      [–]Iconoclast674 0 points1 point  (3 children)

      There are many hormone disrupting chemicals in the water supply. It one thing that has given rise to amphibian and fish to abnormal serial development.

      Here is a paper addressing it's effect on rats: https://www.ncbi.nlm.nih.gov/pubmed/20562219

      The FDA maybe reviewing the regulation, but that doesn't change the science.

      Same could be said about glyphosate and neonics.

      We know they are damaging, science shows us, but USDA would rather take impartial data from the mnufactuers

      [–]latincanuck 0 points1 point  (2 children)

      Again read it, female rats, no estrogen increase in male rats

      [–]Iconoclast674 0 points1 point  (1 child)

      Fair enough;

      However, I think the potential impact on human females is still a reason to be concerned,

      And

      How it impacts the overall human population, or those who come into contact with it the most may vary from rat models.

      Granted thats a bit of conjecture on my part

      [–]latincanuck 0 points1 point  (0 children)

      Right, the question is how much is safe. However the fda did not find anything towards human usage. So far only possible environmental issues due to bacterial resistance

      [–]saint_pill 0 points1 point  (0 children)

      "Along with 36 other researchers, led by vom Saal, the group analyzed hundreds of government-funded studies and found that 90 percent had concluded BPA was a health risk. It was the dozen or so industry-funded studies, vom Saal says, that failed to replicate other BPA research."

      https://www.scientificamerican.com/article/just-how-harmful-are-bisphenol-a-plastics/

      [–]sd4c 0 points1 point  (1 child)

      [–]2InvoluntarySickCunt[S] 2 points3 points  (0 children)

      Fascinating article, thank you for bringing it to my attention. I'm going to dedicate a new top level post to this phenomenon as it seems to be of general interest as well.

      [–]NiceTryDisaster 0 points1 point  (0 children)

      Can someone address the effect of cold showers on testosterone?

      [–]Kalidane 0 points1 point  (0 children)

      Good job man.

      We need more science in here, and a hell of a lot less magical thinking and bullshit.

      [–]prodigy2throw 0 points1 point  (1 child)

      Hilarious how no matter how many upvotes TRP posts get they never get to the front page.

      [–][deleted] 0 points1 point  (0 children)

      Why does water in plastic bottles sometimes taste "plastic-y?"

      [–]drsherbert 0 points1 point  (0 children)

      It's a form of population control. Keep the T levels down and control the birth rate. You can't just eat the red pill on women and take the blue pill in every other facet of life. We always pursue the truth even when it's unpopular. It's deeper than females. We ride or die for this shit.

      [–]i4mn30 0 points1 point  (0 children)

      Pico-unit is by the way 10-12

      [–]I_Need_More_Space_ 0 points1 point  (2 children)

      I think I'll just take the easy route and avoid plastics. Whether it has anything to do with Testosterone, I'll err on the side of caution.

      I think the bigger problem with plastics is that the oceans are suffering a great deal due to toxicity from plastics. Given that the ocean and the organisms that live in the ocean produce 70% of the earth's O2 production, I'd say that that is a bigger issue than a suspected decline in current male testosterone levels.

      To OP, instead of defending plastics in regards to the small scope of direct human impact, try thinking of the bigger picture. The world is not going to miss plastics if they ever go away. The world will however miss the O2 production the oceans provide us if we fuck them up.

      [–]2InvoluntarySickCunt[S] 0 points1 point  (1 child)

      instead of defending plastics in regards to the small scope of direct human impact, try thinking of the bigger picture. The world is not going to miss plastics if they ever go away. The world will however miss the O2 production the oceans provide us if we fuck them up.

      My goal isn't to defend plastics, but rather to make a broader commentary on scientific literacy.

      However, I don't think you realize the vast scope of application of plastics. Sure you can swap out bags for cloth, but in many applications polymers like nylon are unmatched in durability. Furthermore, the o2 in the oceans is a result of photosynthetic cyanobacteria, and I haven't seen any evidence of plastics harming them. if you have it as this is certainly an issue I'm ready to be persuaded on.

      [–]I_Need_More_Space_ 0 points1 point  (0 children)

      Do you not believe that photosynthetic cyanobacteria are part of the vast ocean ecosystem? What affects one part of the ecosystem inherently affects others. You call yourself a scientist.

      You call yourself a scientist. More accurately, you sound like a scientist employed by plastics companies. Cheers to your scientific integrity.

      [–]5t3fan0 0 points1 point  (0 children)

      this is good content, thanks Sickcunt!

      i personally vote the endocrine and hormones topic expecially regarding glucose levels, feast/fast and about how an imbalanced insulin/glucagon can fuck up health and lifts... i believe these to be very important knowledge often disregarded for the sake of simple "calories in/out advice"

      [–]calloberjig 0 points1 point  (0 children)

      Drink water from the sky using a glass vessel

      [–]Bodybuilder1453 0 points1 point  (0 children)

      Thanks. this is very interesting

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